CD97 Antibody

• Background:

  This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

• NCBI Gene ID:

  976

• Swiss Prot:

  P48960

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 240-435 of human CD97 (NP_001775.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Neuroscience, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 105kDa

• Fragment:

  IgG

• Symbol:

  CD97

• Positive Control 2:

  Jurkat

• Positive Control 3:

  Mouse lung

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  CD97 molecule

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CD97, CD97 molecule, Leukocyte antigen CD97, TM7LN1, CD97 antigen

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid