Products for Research Use Only
RegisterLogin

CDC25B (phospho Ser353) Antibody

CAT: 0223-79-999Size: 0.1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-79-999Size:0.1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Cdc25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
NCBI Gene ID
994
Swiss Prot
P30305
Accession Number
NP_001274445.1
Host
Rabbit
Reactivity
Human
Immunogen
CDC25B (phospho Ser353) antibody was raised against a peptide sequence around phosphorylation site of serine 353 (R-R-S (p) -V-T) derived from Human CDC25B .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
64 kDa
Fragment
IgG
Specificity
The antibody detects endogenous level of CDC25B only when phosphorylated at serine 353.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
CDC25B
NCBI Official Name
Cell division cycle 25B
NCBI Organism
Homo sapiens
Background Reference 01
Reboutier D, et al. (2012) J Cell Biol 197, 19-26
Background Reference 02
Lobjois V, et al. (2011) Biochem Biophys Res Commun 410, 87-90
Background Reference 03
Feng C, et al. (2007) Biol Reprod 77, 560-8
Other Product Names
CDC25M2, MPIP2, Dual specificity phosphatase Cdc25B, CDC25HU2
Tested Applications
WB
Protein ID
11641413
Physical Properties
Liquid

Related Products

CatalogName
79-514Cdc25B (phospho Ser149) Antibody
62-765CDC25B Antibody
62-766Cdc25B Antibody
62-767CDC25B Antibody
31-038CDC25B Antibody
29-554CDC25B Antibody
79-118Myc (phospho Ser373) Antibody
79-450Tau (phospho Ser356) Antibody
79-455P90RSK (phospho Ser352) Antibody
79-447P53 (phospho Ser33) Antibody

Alternative Products

CatalogName
MBS8509627-01CDC25B (Phospho-Ser353) Antibody
A0855-01Cdc25B (phospho Ser353) Antibody
CSB-PA570157Phospho-CDC25B (Ser353) Antibody
ABF3257Phospho-CDC25B (Ser353) Antibody
OASG01398-100ULCDC25B Antibody (Phospho-Ser353)
AF3257-BPPhospho-CDC25B (Ser353) Peptide
UB-GEN-16035Cdc25B (phospho Ser353) Polyclonal Antibody
JOT-AP07495-01Cdc25B(Phospho Ser353) Polyclonal Antibody
bs-5245RPhospho-Cdc25B (Ser353) Polyclonal Antibody

Popular Products