FGFR4 (phospho Tyr642) Antibody

• Background:

  Receptor for acidic fibroblast growth factor. Does not bind to basic fibroblast growth factor. Binds FGF19.

• NCBI Gene ID:

  2264

• Swiss Prot:

  P22455

• Accession Number:

  NP_002002.3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  FGFR4 (phospho Tyr642) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 642 (I-D-Y (p) -Y-K) derived from Human FGFR4 .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  90 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of FGFR4 only when phosphorylated at tyrosine 642.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  FGFR4

• NCBI Official Name:

  Fibroblast growth factor receptor 4

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Partanen J.M., EMBO J. 10:1347-1354 (1991) [PubMed: 1709094].

• Background Reference 02:

  Ron D., J. Biol. Chem. 268:5388-5394 (1993) [PubMed: 7680645].

• Background Reference 03:

  Takaishi S., Biochem. Biophys. Res. Commun. 267:658-662 (2000) [PubMed: 10631118].

• Other Product Names:

  FGFR-4, CD_antigen=CD334, Fibroblast growth factor receptor 4, EC=2.7.10.1

• Tested Applications:

  WB

• Protein ID:

  47524173

• Physical Properties:

  Liquid