Tip60 (phospho Ser90) Antibody

• Background:

  The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

• NCBI Gene ID:

  10524

• Swiss Prot:

  Q92993

• Accession Number:

  NP_006379.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p) -P-E) derived from Human Tip60.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  58 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.

• Symbol:

  KAT5

• NCBI Official Name:

  K (lysine) acetyltransferase 5

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kamine J., Virology 216:357-366 (1996) .

• Background Reference 02:

  Sheridan A.M., Mol. Cell. Biol. 21:4470-4481 (2001) .

• Background Reference 03:

  Legube G., Gene 310:161-168 (2003) .

• Other Product Names:

  HTATIP, TI60, Tat-interactive protein-60

• Tested Applications:

  IHC

• Protein ID:

  36287069

• Physical Properties:

  Liquid