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Tip60 (phospho Ser90) Antibody

CAT: 0223-79-924Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-924Size:0.1 mg
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Background
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
NCBI Gene ID
10524
Swiss Prot
Q92993
Accession Number
NP_006379.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tip60 (phospho Ser90) antibody was raised against a peptide sequence around phosphorylation site of Serine 90 (P-G-S (p) -P-E) derived from Human Tip60.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
58 kDa
Fragment
IgG
Specificity
The antibody detects endogenous levels of Tip60 only when phosphorylated at serine 90.
Symbol
KAT5
NCBI Official Name
K (lysine) acetyltransferase 5
NCBI Organism
Homo sapiens
Background Reference 01
Kamine J., Virology 216:357-366 (1996) .
Background Reference 02
Sheridan A.M., Mol. Cell. Biol. 21:4470-4481 (2001) .
Background Reference 03
Legube G., Gene 310:161-168 (2003) .
Other Product Names
HTATIP, TI60, Tat-interactive protein-60
Tested Applications
IHC
Protein ID
36287069
Physical Properties
Liquid

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