MEF2C (phospho Ser396) Antibody

• Background:

  MEF2C transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described.

• NCBI Gene ID:

  4208

• Swiss Prot:

  Q06413

• Accession Number:

  NP_001180279.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  MEF2C (phospho Ser396) antibody was raised against a peptide sequence around phosphorylation site of Serine 396 (P-V-S (p) -P-P) derived from Human MEF2C.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  51 kDa

• Fragment:

  IgG

• Specificity:

  The antibody detects endogenous levels of MEF2C only when phosphorylated at serine 396.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

• Symbol:

  MEF2C

• NCBI Official Name:

  Myocyte enhancer factor 2C

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550 (1993) .

• Background Reference 02:

  McDermott J.C., Mol. Cell. Biol. 13:2564-2577 (1993) .

• Background Reference 03:

  Wang A.H., Mol. Cell. Biol. 19:7816-7827 (1999) .

• Other Product Names:

  Myocyte enhancer factor 2C, Myocyte-specific enhancer factor 2C, Similar to MADS box transcription enhancer factor 2 polypeptide C

• Tested Applications:

  WB, IHC

• Protein ID:

  2500875

• Physical Properties:

  Liquid