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IGFBP 3 Antibody

CAT: 0223-79-770Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-770Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
NCBI Gene ID
3486
Swiss Prot
P17936
Accession Number
NP_001013416.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
IGFBP-3 antibody was raised against a peptide sequence around aa.185~189 (R-Y-K-V-D) derived from Human IGFBP-3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
24 - 41 kDa
Specificity
This antibody detects endogenous level of total IGFBP-3 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
IGFBP3
NCBI Official Name
Insulin-like growth factor binding protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Roghani M., Segovia B., Whitechurch O., Binoux M. Growth Regul. 1:125-130 (1991) Ikonen M., Liu B., Hashimoto Y., Ma L., Lee K. W., Niikura T., Nishimoto I., Cohen P. Proc. Natl. Acad. Sci. U. S. A. 100:13042-13047 (2003) Zhou W., Ross M. M., Tessitore A., Ornstein D., Vanmeter A., Liotta L. A., Petricoin E. F. IIIJ. Proteome Res. 8:5523-5531 (2009)
Other Product Names
IBP3, BP-53, IBP3
Tested Applications
WB
Protein ID
62243248
Physical Properties
Liquid

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