IGFBP-7 Recombinant Protein

• Background:

  Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers.

• NCBI Gene ID:

  3490

• Swiss Prot:

  Q16270-1

• Accession Number:

  NP_001544

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  PBS, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  27 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Insulin-like growth factor-binding protein 7 isoform 1 precursor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Yamauchi T., et al., 1994, Biochem. J. 303:591-598.

• Background Reference 02:

  Oh Y., et al., 1996, J. Biol. Chem. 271:30322-30325.

• Background Reference 03:

  Wilson E.M., et al., 2001, J. Clin. Endocrinol. Metab. 86:4504-4511.

• Other Product Names:

  IBP7, IGFBP7

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3