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WASP Antibody

CAT: 0223-79-733Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-733Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
NCBI Gene ID
7454
Swiss Prot
P42768
Accession Number
NP_000368.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
WASP antibody was raised against a peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
53 kDa
Specificity
This antibody detects endogenous level of total WASP protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
WAS
NCBI Official Name
Wiskott-Aldrich syndrome
NCBI Organism
Homo sapiens
Background Reference 01
Kolluri R., Tolias K. F., Carpenter C. L., Rosen F. S., Kirchhausen T. Proc. Natl. Acad. Sci. U. S. A. 93:5615-5618 (1996) Ramesh N., Anton I. M., Hartwig J. H., Geha R. S. Proc. Natl. Acad. Sci. U. S. A. 94:14671-14676 (1997) Cory G. O. C., Cramer R., Blanchoin L., Ridley A. J. Mol. Cell 11:1229-1239 (2003)
Other Product Names
THC, IMD2, SCNX, THC1, WASP, THC
Tested Applications
WB
Protein ID
4507909
Physical Properties
Liquid

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