Doublecortin Antibody

CAT: 0223-79-731Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0223-79-731Size:0.1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
NCBI Gene ID
1641
Swiss Prot
O43602
Accession Number
NP_000546.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Doublecortin antibody was raised against a peptide sequence around aa.413~417 (P-T-S-P-G) derived from Human Doublecortin.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
40 - 45 kDa
Specificity
This antibody detects endogenous level of total Doublecortin protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
DCX
NCBI Official Name
Doublecortin
NCBI Organism
Homo sapiens
Background Reference 01
Des Portes V., Pinard J. -M., Billuart P., Vinet M. -C., Koulakoff A., Carrie A., Gelot A., Dupuis E., Motte J., Berwald-Netter Y., Catala M., Kahn A., Beldjord C., Chelly J. Cell 92:51-61 (1998) Pilz D. T., Matsumoto N., Minnerath S. R., Mills P., Gleeson J. G., Allen K. M., Walsh C. A., Barkovich A. J., Dobyns W. B., Ledbetter D. H., Ross M. E. Hum. Mol. Genet. 7:2029-2037 (1998)
Other Product Names
DC, DBCN, LISX, SCLH, XLIS, DCX, DC
Tested Applications
WB
Protein ID
30181246
Physical Properties
Liquid

Related Products

CatalogName
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
63-397TLK1 Antibody
63-400WEE1 Antibody
63-411UCK Antibody
63-413AK3 Antibody
63-414AK3 Antibody
63-416PFKP Antibody
63-421HK2 Antibody

Alternative Products

CatalogName
MBS8583482-01Doublecortin Antibody

Popular Products