ERAB Antibody

CAT: 0223-79-705Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0223-79-705Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) .
NCBI Gene ID
3028
Swiss Prot
Q99714
Accession Number
NP_004484.1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ERAB antibody was raised against a peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
27 kDa
Specificity
This antibody detects endogenous level of total ERAB protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
HSD17B10
NCBI Official Name
Hydroxysteroid (17-beta) dehydrogenase 10
NCBI Organism
Homo sapiens
Background Reference 01
Holzmann J., Frank P., Loeffler E., Bennett K. L., Gerner C., Rossmanith W. Cell 135:462-474 (2008)
Other Product Names
ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22, ABAD
Tested Applications
WB
Protein ID
4758504
Physical Properties
Liquid

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