GluR1 Antibody

• Background:

  Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  2890

• Swiss Prot:

  P42261

• Accession Number:

  NP_000818.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  GluR1 antibody was raised against a peptide sequence around aa. 831~835 (K-S-R-S-E) derived from Human GluR1 .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  110 kDa

• Specificity:

  This antibody detects endogenous levels of total GluR1 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  GRIA1

• NCBI Official Name:

  Glutamate receptor, ionotropic, AMPA 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Emamian ES, et al. (2004) J Neurosci. 24 (7) : 1561-4Palmer, C. L. et al. (2005) Pharmacol. Rev. 57, 253-277.

• Other Product Names:

  GLUH1, GLUR1, GLURA, GluA1, HBGR1, GLR1, GLUH1, GRIA1, GluR-1, GluR-A

• Tested Applications:

  WB

• Protein ID:

  167001419

• Physical Properties:

  Liquid