GluR1 Antibody

CAT: 0223-79-701Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0223-79-701Size:0.1 mg
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Background
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
2890
Swiss Prot
P42261
Accession Number
NP_000818.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
GluR1 antibody was raised against a peptide sequence around aa. 831~835 (K-S-R-S-E) derived from Human GluR1 .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
110 kDa
Specificity
This antibody detects endogenous levels of total GluR1 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
GRIA1
NCBI Official Name
Glutamate receptor, ionotropic, AMPA 1
NCBI Organism
Homo sapiens
Background Reference 01
Emamian ES, et al. (2004) J Neurosci. 24 (7) : 1561-4Palmer, C. L. et al. (2005) Pharmacol. Rev. 57, 253-277.
Other Product Names
GLUH1, GLUR1, GLURA, GluA1, HBGR1, GLR1, GLUH1, GRIA1, GluR-1, GluR-A
Tested Applications
WB
Protein ID
167001419
Physical Properties
Liquid

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