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ASH2L Antibody

CAT: 0223-79-687Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-687Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.
NCBI Gene ID
9070
Swiss Prot
Q9UBL3
Accession Number
NP_004665.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ASH2L antibody was raised against a peptide sequence around aa.620~624 (G-R-R-S-P) derived from Human ASH2L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
65, 80 kDa
Specificity
This antibody detects endogenous level of total ASH2L protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
ASH2L
NCBI Official Name
Ash2 (absent, small, or homeotic) -like (Drosophila)
NCBI Organism
Homo sapiens
Background Reference 01
Wysocka J., Myers M. P., Laherty C. D., Eisenman R. N., Herr W. Genes Dev. 17:896-911 (2003) Patel A., Dharmarajan V., Vought V. E., Cosgrove M. S. J. Biol. Chem. 284:24242-24256 (2009)
Other Product Names
ASH2, Bre2, ASH2L1, ASH2L2, ASH2
Tested Applications
WB
Protein ID
157412280
Physical Properties
Liquid

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