CD44 Antibody

• Background:

  Receptor for hyaluronic acid (HA) . Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

• NCBI Gene ID:

  960

• Swiss Prot:

  P16070

• Accession Number:

  NP_000601.3

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  CD44 antibody was raised against a peptide sequence around aa.734~738 (Q-N-V-D-M) derived from Human CD44.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  80 kDa

• Specificity:

  This antibody detects endogenous level of total CD44 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  CD44

• NCBI Official Name:

  CD44 molecule (Indian blood group)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Teriete P., et. al (2004) Mol. Cell 13:483-496 Bartolazzi A. (2003) Melanoma Res. 13:325-337Liu T. et. al (2005) J. Proteome Res. 4:2070-2080

• Other Product Names:

  IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III

• Tested Applications:

  WB

• Protein ID:

  48255935

• Physical Properties:

  Liquid