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CD44 Antibody

CAT: 0223-79-668Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-668Size:0.1 mg
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Background
Receptor for hyaluronic acid (HA) . Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs) . Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
NCBI Gene ID
960
Swiss Prot
P16070
Accession Number
NP_000601.3
Host
Rabbit
Reactivity
Human, Rat
Immunogen
CD44 antibody was raised against a peptide sequence around aa.734~738 (Q-N-V-D-M) derived from Human CD44.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
80 kDa
Specificity
This antibody detects endogenous level of total CD44 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
CD44
NCBI Official Name
CD44 molecule (Indian blood group)
NCBI Organism
Homo sapiens
Background Reference 01
Teriete P., et. al (2004) Mol. Cell 13:483-496 Bartolazzi A. (2003) Melanoma Res. 13:325-337Liu T. et. al (2005) J. Proteome Res. 4:2070-2080
Other Product Names
IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III
Tested Applications
WB
Protein ID
48255935
Physical Properties
Liquid

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