CD44 Antibody [KM201]

• Background:

  CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.

• NCBI Gene ID:

  12505

• Swiss Prot:

  P15379

• Accession Number:

  P15379

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  (C57BL/6 x DBA/2) F1 mouse bone marrow-derived stromal clone BMS2

• Clonality:

  Monoclonal

• Clone:

  [KM201]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG1

• Specificity:

  CD44

• Applications Notes:

  CD44 Antibody [KM201] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, blocking, and adhesion assays.

• Symbol:

  Cd44

• NCBI Official Name:

  CD44 antigen

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Pgp-1, H-CAM, HUTCH-1, ECMR-III

• Tested Applications:

  ELISA, WB, IHC-P, ICC

• Physical Properties:

  Liquid