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ASPSCR1 Antibody

CAT: 0223-79-649Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-649Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.
NCBI Gene ID
79058
Swiss Prot
Q9BZE9
Accession Number
NP_076988.1
Host
Rabbit
Reactivity
Human
Immunogen
ASPSCR1 antibody was raised against a peptide sequence around aa.303 ~307 (P-Q-Q-E-Q) derived from Human ASPSCR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
70 - 75 kDa
Specificity
This antibody detects endogenous levels of total ASPSCR1 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
ASPSCR1
NCBI Official Name
Alveolar soft part sarcoma chromosome region, candidate 1
NCBI Organism
Homo sapiens
Background Reference 01
Ladanyi, M. et al. (2001) Oncogene 20, 48-57. Bogan, J. S. et al. (2003) Nature 425, 727-33. Yu, C. et al. (2007) J Biol Chem 282, 7710-22.
Other Product Names
TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9, ASPCR1, HSP27, HSP28, TUG
Tested Applications
WB
Protein ID
13129078
Physical Properties
Liquid

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