LC3 Antibody

• Background:

  Probably involved in formation of autophagosomal vacuoles (autophagosomes) .

• NCBI Gene ID:

  84557

• Swiss Prot:

  Q9H492

• Accession Number:

  NP_115903.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  LC3 antibody was raised against a peptide sequence around aa. 112-116 (V-Y-A-S-Q) derived from Human LC3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  19 kDa

• Specificity:

  This antibody detects endogenous level of total LC3 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  MAP1LC3A

• NCBI Official Name:

  Microtubule-associated protein 1 light chain 3 alpha

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  He H., Dang Y., Dai F., Guo Z., Wu J., She X., Pei Y., Chen Y., Ling W., Wu C., Zhao S., Liu J. O., Yu L. J. Biol. Chem. 278:29278-29287 (2003) Tanida I., Sou Y. -S., Ezaki J., Minematsu-Ikeguchi N., Ueno T., Kominami E. J. Biol. Chem. 279:36268-36276 (2004)

• Other Product Names:

  LC3, LC3A, ATG8E, MAP1ALC3, MAP1BLC3

• Tested Applications:

  WB

• Protein ID:

  14210522

• Physical Properties:

  Liquid