Cdc25A (Ab 76) Antibody

• Background:

  Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

• NCBI Gene ID:

  993

• Swiss Prot:

  P30304

• Accession Number:

  NP_001780.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Cdc25A (Ab-76) antibody was raised against a peptide sequence around aa. 73~77 (M-G-S-S-E) derived from Human cdc25A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  70 kDa

• Specificity:

  This antibody detects endogenous level of total cdc25A protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  CDC25A

• NCBI Official Name:

  Cell division cycle 25A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jin J, et al. (2003) Genes 17 (24) : 3062-74. Shimuta K, et al. (2002) EMBO J 21 (14) : 3694-703.

• Other Product Names:

  CDC25A2, CDC25M3, MPIP1

• Tested Applications:

  WB

• Protein ID:

  42490758

• Physical Properties:

  Liquid