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CD144 Antibody [BV13] (PE)

CAT: 0223-76-864Size: 0.025 mgDry Ice: NoHazardous: No
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CAT#:0223-76-864Size:0.025 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The BV13 monoclonal antibody specifically reacts with mouse CD144 (VE-Cadherin), a 120 kDA type II Cadherin. CD144 is a hemophilic adhesion molecule of the endothelial cell line essential to maintaining cell layer integrity. It is involved in cell growth inhibition, migration, and survival.
NCBI Gene ID
12562
Swiss Prot
P55284
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
BV13
Conjugation
PE
Type
Primary Antibodies
Field of Research
Cancer
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Rat IgG1, kappa
Specificity
The BV13 monoclonal antibody specifically reacts with mouse CD144 (VE-Cadherin), a 120 kDA type II Cadherin.
Symbol
Cdh5
NCBI Official Name
Cadherin 5
NCBI Organism
Mus musculus
Background Reference 01
Noelle, R. J., Roy, M., Shepherd, D. M., Stamenkovic, I., Ledbetter, J. A., Aruffo, A. (1992) . A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells.Proceedings of the National Academy of Sciences,89 (14), 6550-6554.
Background Reference 02
Roy, M., Aruffo, A., Ledbetter, J., Linsley, P., Kehry, M., Noelle, R. (1995) . Studies on the interdependence of gp39 and B7 expression and function during antigen‐specific immune responses.European journal of immunology,25 (2), 596-603.
Background Reference 03
Van den Eertwegh, A. J., Noelle, R. J., Roy, M. E. E. N. A. K. S. H. I., Shepherd, D. M., Aruffo, A., Ledbetter, J. A., ... Claassen, E. (1993) . In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate TB cell interactions.The Journal of experimental medicine,178 (5), 1555-1565.
Other Product Names
7B4, Vec, VECD, Cd144, VEcad, VE-Cad, AA408225, Cdh5
Tested Applications
Flow
Physical Properties
Liquid

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