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CD184 Antibody [2B11] (PE)

CAT: 0223-76-872Size: 0.05 mgDry Ice: NoHazardous: No
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CAT#:0223-76-872Size:0.05 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.
NCBI Gene ID
12767
Swiss Prot
P70658
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
2B11
Conjugation
PE
Type
Primary Antibodies
Field of Research
Stem Cell, Chemokines & Cytokines, Growth Factors
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Rat IgG2b, kappa
Specificity
The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor.
Symbol
Cxcr4
NCBI Official Name
Chemokine (C-X-C motif) receptor 4
NCBI Organism
Mus musculus
Background Reference 01
Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., Leone, G. (2001) . CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia lymphoma,42 (6), 1195-1206.
Background Reference 02
She, X., Matsuno, F., Harada, N., Tsai, H., Seon, B. K. (2004) . Synergy between anti‐endoglin (CD105) monoclonal antibodies and TGF‐-beta in suppression of growth of human endothelial cells.International journal of cancer,108 (2), 251-257.
Background Reference 03
Seon, B. K., Kumar, S. (2002) . CD105 antibody for targeting of tumor vascular endothelial cells. InThe new angiotherapy (pp. 499-515) . Humana Press.
Other Product Names
CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1
Tested Applications
Flow
Physical Properties
Liquid

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