CD31 Antibody [390]

• Background:

  The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) . CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction.

• NCBI Gene ID:

  18613

• Swiss Prot:

  Q08481

• Host:

  Rat

• Reactivity:

  Mouse

• Clonality:

  Monoclonal

• Clone:

  390

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies

• Field of Research:

  Cancer

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C . Do not freeze.

• Fragment:

  Rat IgG2a, kappa

• Specificity:

  The 390 monoclonal antibody specifically reacts with mouse cd31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) .

• Symbol:

  Pecam1

• NCBI Official Name:

  Platelet/endothelial cell adhesion molecule 1

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  HORENSTEIN, A., STOCKINGER, H., Imhof, B., MALAVASI, F. (1998) . CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J,330, 1129-1135.

• Background Reference 02:

  Baldwin, H. S., Shen, H. M., Yan, H. C., DeLisser, H. M., Chung, A., Mickanin, C., ... Albelda, S. M. (1994) . Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) : alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development.Development,120 (9), 2539-2553.

• Background Reference 03:

  DeLisser, H. M., Christofidou-Solomidou, M., Strieter, R. M., Burdick, M. D., Robinson, C. S., Wexler, R. S., ... Albelda, S. M. (1997) . Involvement of endothelial PECAM-1/CD31 in angiogenesis.The American journal of pathology,151 (3), 671.

• Other Product Names:

  Cd31, Pecam, C85791, PECAM-1, Pecam1

• Tested Applications:

  Flow, Functional Assays

• Physical Properties:

  Liquid