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CD20 Antibody [2H7]

CAT: 0223-76-005Size: 0.025 mgDry Ice: NoHazardous: No
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CAT#:0223-76-005Size:0.025 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule. CD20 is an unglycosylated four-transmembrane phosphoprotein expressed by B cells in all stage of development, except the final plasma cells. It has been reported that the molecule is involved in B cell activation and has also been observed on a subset of circulating T lymphocytes.
NCBI Gene ID
931
Swiss Prot
P11836
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
2H7
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Fragment
Mouse IgG2b, kappa
Specificity
The 2H7 monoclonal antibody specifically reacts with human CD20, a 33-37kDA B-lymphocyte surface molecule.
Symbol
MS4A1
NCBI Official Name
Membrane-spanning 4-domains, subfamily A, member 1
NCBI Organism
Homo sapiens
Background Reference 01
Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 02
Polyak, M. J., Deans, J. P. (2002) . Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes
Background Reference 03
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Other Product Names
B1, S7, Bp35, CD20, CVID5, MS4A2, LEU-16, MS4A1
Tested Applications
Flow, IHC
Physical Properties
Liquid

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