EGFR (Ab 1070) Antibody

• Background:

  Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

• NCBI Gene ID:

  1956

• Swiss Prot:

  P00533

• Accession Number:

  NP_005219.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  EGFR (Ab-1070) antibody was raised against a peptide sequence around aa.1068~1072 (R-Y-S-S-D) derived from Human EGFR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  175 kDa

• Specificity:

  This antibody detects endogenous level of total EGFR protein.

• Applications Notes:

  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

• Symbol:

  EGFR

• NCBI Official Name:

  Epidermal growth factor receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Feinmesser RL, et al. (1999) J Biol Chem; 274 (23) : 16168-73. Gamou S, et al. (1995) FEBS Lett; 357 (2) : 161-4. Gamou S, et al. (1994) J Cell Physiol; 158 (1) : 151-9. Heisermann GJ, et al. (1988) J Biol Chem; 263 (26) : 13152-8.

• Other Product Names:

  ERBB, HER1, mENA, ERBB1, PIG61, GLUH1, GLUR1, Receptor tyrosine-protein kinase ErbB-1

• Tested Applications:

  WB, IHC, IF

• Protein ID:

  29725609

• Physical Properties:

  Liquid