TLN2 Antibody

• Background:

  Talin 2 [Homo sapiens]. Talin 2 is related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.

• NCBI Gene ID:

  83660

• Swiss Prot:

  Q9Y4G6

• Accession Number:

  NP_055874.1

• Host:

  Chicken

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  1750-1950

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Antigen affinity-purified

• Concentration:

  1 mg/mL

• Buffer:

  Phosphate-Buffered Saline. No preservatives added.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  TLN2 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  271.6 kDa (calculated)

• Applications Notes:

  TLN2 antibody can be used for the detection of TLN2 by Western blot, may also work for IHC and ICC.

• Symbol:

  TLN2

• NCBI Official Name:

  Talin 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Di Paolo, G., Pellegrini, L., Letinic, K., Cestra, G., Zoncu, R., Voronov, S., Chang, S., Guo, J., Wenk, M. R., De Camill, P., Recruitment and regulation of phosphatidylinositol phosphate kinase type I-gamma by the FERM domain of talin. Nature 420: 85-89, 2002.

• Other Product Names:

  KIAA0320, Talin-2, ILWEQ

• Tested Applications:

  WB

• Protein ID:

  22035665

• Physical Properties:

  Liquid