M6PR Antibody

CAT: 223-XW-7358Size: 0.05 mgDry Ice: NoHazardous: No
0.05 mgSelected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Chicken polyclonal IgY Antibodies against cation-dependent mannose-6-phosphate receptor. This protein is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein that localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane.
NCBI Gene ID
4074
Swiss Prot
P20645
Accession Number
NP_002346.1
Host
Chicken
Reactivity
Human, Mouse, Rat
Immunogen
60-114
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antigen affinity-purified
Concentration
1 mg/mL
Buffer
Phosphate-Buffered Saline. No preservatives added.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
M6PR antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa (calculated)
Applications Notes
M6PR antibody can be used for the detection of M6PR by ICC, may also work for IHC.
Symbol
M6PR
NCBI Official Name
Mannose-6-phosphate receptor (cation dependent)
NCBI Organism
Homo sapiens
Background Reference 01
Klumperman, J. et al. Differences in the endosomal distributions of the two mannose 6-phosphate receptors J. Cell Biol. 121 (5), 997-1010 (1993)
Other Product Names
MPR46, MPRD, Cation-dependent mannose-6-phosphate receptor, 46 kDa mannose 6-phosphate receptor, CD Man-6-P receptor, SMPR, MPR46, CD-MPR, MPR 46, MPR-46
Tested Applications
ICC
Protein ID
4505061
Physical Properties
Liquid