IL1A Antibody

• Background :

  Interleukin 1, α proprotein. IL-1α is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding this protein and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.

• NCBI Gene ID :

  3552

• Swiss Prot :

  P01583

• Accession Number :

  NP_000566.1

• Host :

  Chicken

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  1-271

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Chemokines & Cytokines

• Purification :

  Antigen affinity-purified

• Concentration :

  1 mg/mL

• Buffer :

  Phosphate-Buffered Saline. No preservatives added.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  IL1A antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  30.6 kDa (calculated)

• Applications Notes :

  IL-1a antibody can be used for the detection of IL-1a by Western blot, may also work for IHC and ICC.

• Symbol :

  IL1A

• NCBI Official Name :

  Interleukin 1, alpha

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Sabatino, M., Boyce, B., Aufdemorte, T., Bonewald, L., Mundy, G. R. Infusions of recombinant human interleukins 1 alpha and 1 beta cause hypercalcemia in normal mice. Proc. Nat. Acad. Sci. 85: 5235-5239, 1988.

• Other Product Names :

  IL1F1, Interleukin-1 alpha, Hematopoietin-1, IL-1 alpha, IL1, IL-1A, IL1F1, IL1-ALPHA

• Tested Applications :

  WB

• Protein ID :

  13236494

• Physical Properties :

  Liquid