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S100A Antibody [2C8B8 / 2C8E8]

CAT: 0223-32-213Size: 0.1 mLDry Ice: NoHazardous: No
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CAT#:0223-32-213Size:0.1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
S100 calcium binding protein A1 (S100-alpha/ S100A1), The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.
NCBI Gene ID
6271
Swiss Prot
P23297
Accession Number
P23297
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified truncated recombinant S100A expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
2C8B8 / 2C8E8
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A affinity chromatography.
Concentration
Batch dependent
Buffer
Ascitic fluid containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
S100A monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG1
Symbol
S100A1
NCBI Official Name
S100 calcium binding protein A1
NCBI Organism
Homo sapiens
Background Reference 01
Koenig A, Wojcieszyn J, Weeks BR, et al. Vet Pathol. 2001;38 (4) :427-35.
Background Reference 02
Hoyaux D, Decaestecker C, Heizmann CW, et al. Brain Res. 2000;867 (1-2) :280-8.
Background Reference 03
Pingerelli PL, Mizukami H, Wagner AS, et al. J Protein Chem. 1990;9 (2) :169-75.
Other Product Names
S100A, S-100 protein alpha chainS100, S100A, S100-alpha
Tested Applications
ELISA
Protein ID
134136

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