S100A8 & S100A9 Heterodimer Recombinant Protein

• Background:

  S100A8 is a member of the S100 family, EF-hand superfamily of Ca-binding proteins. It is produced by neutrophils and monocytes, and forms Ca2+-dependent heterodimer/heterotetramer complexes (termed calprotectin) with S100A9. Calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase.

• NCBI Gene ID:

  6279

• Swiss Prot:

  P05109 , P06702

• Accession Number:

  P05109 , P06702

• Tag:

  C-6 His tag

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Signal Transduction

• Buffer:

  Supplied as a 0.2 um filtered solution of 20mM HEPES,10%Glycerol,150mM NaCl,2.5mM EDTA, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

• Shipping Conditions:

  Dry Ice

• Calculated Molecular Weight:

  11.7 and 13.2 kD

• Applications Notes:

  This recombinant protein can be used for biological assays. For research use only.

• NCBI Official Name:

  S100 calcium binding protein A8

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  S100A8/S100A9 Heterodimer

• Species:

  Human

• Physical Properties:

  Liquid

• CAS Number:

  9000-83-3