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Rab25 Antibody [3F12F3]

CAT: 0223-32-208Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-32-208Size:0.1 mg
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Background
Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa.
NCBI Gene ID
57111
Swiss Prot
P57735
Accession Number
P57735
Host
Mouse
Reactivity
Human
Immunogen
Ni-NTA purified recombinant Rab25 expressed in E. Coli strain BL21 (DE3) .
Clonality
Monoclonal
Clone
3F12F3
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
Antibody is purified by protein A affinity chromatography and resuspended in PBS with 0.2%BSA, 0.09% sodium azide.
Concentration
Batch dependent
Buffer
Purified antibody in PBS containing 0.03% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Rab25 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG2a
Symbol
RAB25
NCBI Official Name
RAB25, member RAS oncogene family
NCBI Organism
Homo sapiens
Background Reference 01
JR Goldenring, KR Shen, HD Vaughan. et al. J. Biol. Chem,1993,268 (25) :18419-18422
Background Reference 02
Xiaoye W, Ravindra K, Jennifer N. et al. J. Biol. Chem,2000,275 (37) :29138-29146
Other Product Names
CATX8, CATX-8CATX-8, RAB11C
Tested Applications
ELISA, WB, IHC
Protein ID
46577696