RAB25 Antibody

• Background:

  RAB proteins, such as RAB25, are members of the RAS superfamily of small GTPases that are involved in membrane trafficking. Members of the RAB11 subfamily, including RAB25, control the return of internalized membrane-associated moieties to the cell surface (Caswell et al., 2007 [PubMed 17925226]) .[supplied by OMIM].

• NCBI Gene ID:

  57111

• Swiss Prot:

  P57735

• Accession Number:

  P57735

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This RAB25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-141 amino acids from the Central region of human RAB25.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rb

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  23 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RAB25

• NCBI Official Name:

  Ras-related protein Rab-25

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cheng, J.M., et al. Int. J. Cancer 126 (12) :2799-2812 (2010)

• Background Reference 02:

  Nam, K.T., et al. J. Clin. Invest. 120 (3) :840-849 (2010)

• Background Reference 03:

  Caswell, P.T., et al. Dev. Cell 13 (4) :496-510 (2007)

• Background Reference 04:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :

• Other Product Names:

  Ras-related protein Rab-25, CATX-8, RAB25, CATX8

• Tested Applications:

  WB

• Protein ID:

  46577696

• Physical Properties:

  Liquid