SPDYA Antibody

• Background:

  SPDYA (speedy homolog A (Drosophila) ) regulates the G1/S phase transition of the cell cycle by binding and activating CDC2, CDK2 and CDKN1B/KIP1. SPDYA can activate CDK2 without promoting CDK2 phosphorylation. SPDYA mediates cell survival during the DNA damage process through activation of CDK2.

• NCBI Gene ID:

  245711

• Swiss Prot:

  Q5MJ70

• Accession Number:

  Q5MJ70

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SPDYA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human SPDYA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SPDYA

• NCBI Official Name:

  Speedy protein A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ke, Q., et al. Exp. Mol. Pathol. 87 (3) :167-172 (2009)

• Background Reference 02:

  Dinarina, A., et al. FEBS Lett. 583 (17) :2772-2778 (2009)

• Background Reference 03:

  McAndrew, C.W., et al. Cell Cycle 8 (1) :66-75 (2009)

• Other Product Names:

  HGNC:30613

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  94730574

• Physical Properties:

  Liquid