PLA2G6 Antibody

• Background:

  The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells.

• NCBI Gene ID:

  8398

• Swiss Prot:

  O60733

• Accession Number:

  O60733

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PLA2G6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-580 amino acids from the Central region of human PLA2G6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  90 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PLA2G6

• NCBI Official Name:

  85/88 kDa calcium-independent phospholipase A2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ayilavarapu, S., et al. J. Immunol. 184 (3) :1507-1515 (2010) Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010) Tan, E.K., et al. Ann. Neurol. 67 (1), 148 (2010) Hosgood, H.D. III, et al. Respir Med 103 (12) :1866-1870 (2009)

• Other Product Names:

  85/88 kDa calcium-independent phospholipase A2, CaI-PLA2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-containing protein 9, PNPLA9, PLA2G6, PLPLA9

• Tested Applications:

  WB, IHC-P, IF, Flow

• Physical Properties:

  Liquid