PLA2G7 Antibody

• Background:

  The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency.

• NCBI Gene ID:

  7941

• Swiss Prot:

  Q13093

• Accession Number:

  Q13093

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PLA2G7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human PLA2G7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  50 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PLA2G7

• NCBI Official Name:

  Platelet-activating factor acetylhydrolase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Fan, P., et al. Hum. Reprod. 25 (5) :1288-1294 (2010)

• Background Reference 02:

  Paik, J.K., et al. Clin. Chim. Acta 411 (7-8), 486-493 (2010)

• Background Reference 03:

  Meng, X., et al. Psychiatry Res 175 (1-2), 186-187 (2010)

• Background Reference 04:

  McGeachie, M., et al. Circulation 120 (24) :2448-2454 (2009)

• Other Product Names:

  Platelet-activating factor acetylhydrolase, PAF acetylhydrolase, 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA (2), PAF 2-acylhydrolase, PLA2G7, PAFAH

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  2497687

• Physical Properties:

  Liquid