PYCR1 Antibody

• Background:

  This gene encodes an enzyme that catalyzes the NAD (P) H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP (+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.

• NCBI Gene ID:

  5831

• Swiss Prot:

  P32322

• Accession Number:

  P32322

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  33 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  PYCR1

• NCBI Official Name:

  Pyrroline-5-carboxylate reductase 1, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Reversade, B., et al. Nat. Genet. 41 (9) :1016-1021 (2009)

• Background Reference 02:

  Guernsey, D.L., et al. Am. J. Hum. Genet. 85 (1) :120-129 (2009)

• Background Reference 03:

  Meng, Z., et al. J. Mol. Biol. 359 (5) :1364-1377 (2006)

• Other Product Names:

  Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, PYCR1

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  60416434

• Physical Properties:

  Liquid