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ADCY4 Antibody

CAT: 0223-64-161Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-161Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP) . Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
NCBI Gene ID
196883
Swiss Prot
Q8NFM4
Accession Number
Q8NFM4
Host
Rabbit
Reactivity
Human
Immunogen
This ADCY4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-441 amino acids from the Central region of human ADCY4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
120 kDa
Fragment
Rabbit Ig
Symbol
ADCY4
NCBI Official Name
Adenylate cyclase type 4
NCBI Organism
Homo sapiens
Background Reference 01
Rhim, J.H., et al. Aging Cell 5 (6) :451-461 (2006)
Background Reference 02
Jiang, G., et al. Am. J. Physiol. Endocrinol. Metab. 284 (4), E671-E678 (2003)
Background Reference 03
Sunahara, R.K., et al. Mol. Interv. 2 (3) :168-184 (2002)
Background Reference 04
Ludwig, M.G., et al. J. Recept. Signal Transduct. Res. 22 (1-4), 79-110 (2002)
Other Product Names
Adenylate cyclase type 4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4, ADCY4
Tested Applications
WB, Flow
Protein ID
25008336
Physical Properties
Liquid

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