Products for Research Use Only

K2C78 Antibody

CAT: 0223-64-150Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-150Size:400 µL
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Background
This gene is a member of the type II keratin gene family and encodes a protein with an intermediate filament domain. Keratins are the major structural proteins in epithelial cells, forming a cytoplasmic network of 10 to 12 nm wide intermediate filaments and creating a scaffold that gives cells the ability to withstand mechanical and non-mechanical stresses. The genes of the type II keratin family are located as a gene cluster at 12p13.13. Four pseudogenes of this gene family have been identified.
NCBI Gene ID
196374
Swiss Prot
Q8N1N4
Accession Number
Q8N1N4
Host
Rabbit
Reactivity
Human
Immunogen
This K2C78 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the Central region of human K2C78.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
KRT78
NCBI Official Name
Keratin, type II cytoskeletal 78
NCBI Organism
Homo sapiens
Background Reference 01
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007)
Background Reference 02
Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)
Background Reference 03
Rogers, M.A., et al. J. Invest. Dermatol. 124 (3) :536-544 (2005)
Background Reference 04
Hesse, M., et al. Eur. J. Cell Biol. 83 (1) :19-26 (2004)
Other Product Names
Keratin, type II cytoskeletal 78, Cytokeratin-78, CK-78, Keratin-5b, Keratin-78, K78, Type-II keratin Kb40, KRT78, K5B, KB40
Tested Applications
WB, Flow
Protein ID
166218809
Physical Properties
Liquid