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ATP5A1 Antibody

CAT: 0223-64-109Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-109Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, using an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c) . This gene encodes the alpha subunit of the catalytic core.
NCBI Gene ID
498
Swiss Prot
P25705
Accession Number
P25705
Host
Rabbit
Reactivity
Human
Immunogen
This ATP5A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-503 amino acids from the C-terminal region of human ATP5A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Symbol
ATP5A1
NCBI Official Name
ATP synthase subunit alpha, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Pandey, N.R., et al. Am. J. Pathol. 175 (4) :1777-1787 (2009)
Background Reference 02
Seth, R., et al. J. Clin. Pathol. 62 (7) :598-603 (2009)
Background Reference 03
Law, I.K., et al. Proteomics 9 (9) :2444-2456 (2009)
Background Reference 04
Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009)
Other Product Names
ATP synthase subunit alpha, mitochondrial, ATP5A1, ATP5A, ATP5AL2, ATPM
Tested Applications
WB, IHC-P
Protein ID
114517
Physical Properties
Liquid

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