ST8SIA4 Antibody

• Background:

  The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1) . The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus.

• NCBI Gene ID:

  7903

• Swiss Prot:

  Q92187

• Accession Number:

  Q92187

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This ST8SIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the Central region of human ST8SIA4.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  41 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ST8SIA4

• NCBI Official Name:

  CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Johnson, M.P., et al. Hum. Genet. 126 (5) :655-666 (2009)

• Background Reference 02:

  Foley, D.A., et al. J. Biol. Chem. 284 (23) :15505-15516 (2009)

• Background Reference 03:

  Otowa, T., et al. J. Hum. Genet. 54 (2) :122-126 (2009)

• Background Reference 04:

  Sonuga-Barke, E.J., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (8), 1359-1368 (2008) :

• Other Product Names:

  CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase, 2499-, Alpha-2,8-sialyltransferase 8D, Polysialyltransferase-1, Sialyltransferase 8D, SIAT8-D, Sialyltransferase St8Sia IV, ST8SiaIV, ST8SIA4, PST, PST1, SIAT8D

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  2494834

• Physical Properties:

  Liquid