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SGMS2 Antibody

CAT: 0223-64-088Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-088Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. SGMS2 is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. This protein is required for cell growth.
NCBI Gene ID
166929
Swiss Prot
Q8NHU3
Accession Number
Q8NHU3
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This SGMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SGMS2
NCBI Official Name
Phosphatidylcholine:ceramide cholinephosphotransferase 2
NCBI Organism
Homo sapiens
Background Reference 01
Ternes, P., et al. J. Lipid Res. 50 (11) :2270-2277 (2009)
Background Reference 02
Liu, J., et al. Arterioscler. Thromb. Vasc. Biol. 29 (6) :850-856 (2009)
Background Reference 03
Tani, M., et al. Biochem. Biophys. Res. Commun. 381 (3) :328-332 (2009)
Other Product Names
Phosphatidylcholine:ceramide cholinephosphotransferase 2, Sphingomyelin synthase 2, SGMS2, SMS2
Tested Applications
WB
Protein ID
44888519
Physical Properties
Liquid

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