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KRT1 Antibody

CAT: 0223-64-066Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-066Size:400 µL
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Background
KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.
NCBI Gene ID
3848
Swiss Prot
P04264
Accession Number
P04264
Host
Rabbit
Reactivity
Human
Immunogen
This KRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of human KRT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
66 kDa
Fragment
Rabbit Ig
Symbol
KRT1
NCBI Official Name
Keratin, type II cytoskeletal 1
NCBI Organism
Homo sapiens
Background Reference 01
Labudova, M., et al. J. Virol. 83 (16) :7842-7849 (2009)
Background Reference 02
Barcelos, A.C., et al. J. Cutan. Pathol. 36 (6) :647-654 (2009)
Background Reference 03
Grimberg, G., et al. Br. J. Dermatol. 160 (2) :446-449 (2009)
Other Product Names
Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA
Tested Applications
WB, IHC-P, Flow
Protein ID
238054406
Physical Properties
Liquid

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