KRT1 Antibody

• Background:

  KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

• NCBI Gene ID:

  3848

• Swiss Prot:

  P04264

• Accession Number:

  P04264

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of human KRT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  66 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KRT1

• NCBI Official Name:

  Keratin, type II cytoskeletal 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Labudova, M., et al. J. Virol. 83 (16) :7842-7849 (2009)

• Background Reference 02:

  Barcelos, A.C., et al. J. Cutan. Pathol. 36 (6) :647-654 (2009)

• Background Reference 03:

  Grimberg, G., et al. Br. J. Dermatol. 160 (2) :446-449 (2009)

• Other Product Names:

  Keratin, type II cytoskeletal 1, 67 kDa cytokeratin, Cytokeratin-1, CK-1, Hair alpha protein, Keratin-1, K1, Type-II keratin Kb1, KRT1, KRTA

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  238054406

• Physical Properties:

  Liquid