KRT19 Antibody

• Background:

  KRT19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

• NCBI Gene ID:

  3880

• Swiss Prot:

  P08727

• Accession Number:

  P08727

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KRT19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human KRT19.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KRT19

• NCBI Official Name:

  Keratin, type I cytoskeletal 19

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bonzanini, M., Acta Cytol. 52 (5), 541-548 (2008)

• Background Reference 02:

  Yang, X.R., Clin. Cancer Res. 14 (12), 3850-3859 (2008)

• Background Reference 03:

  Maurer, J., PLoS ONE (10), E3451 (2008)

• Other Product Names:

  Keratin, type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19

• Tested Applications:

  WB, IHC-P

• Protein ID:

  311033484

• Physical Properties:

  Liquid