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KCE1L Antibody

CAT: 0223-64-057Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-64-057Size:400 µL
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a membrane protein which has sequence similarity to the KCNE1 gene product, a member of the potassium channel, voltage-gated, isk-related subfamily. This intronless gene is deleted in AMME contiguous gene syndrome and may be involved in the cardiac and neurologic abnormalities found in the AMME contiguous gene syndrome.
NCBI Gene ID
23630
Swiss Prot
Q9UJ90
Accession Number
Q9UJ90
Host
Rabbit
Reactivity
Human
Immunogen
This KCE1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the Central region of human KCE1L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNE1L
NCBI Official Name
Potassium voltage-gated channel subfamily E member 1-like protein
NCBI Organism
Homo sapiens
Background Reference 01
Ravn, L.S., et al. Heart Rhythm 5 (3) :427-435 (2008)
Background Reference 02
Lundquist, A.L., et al. Genomics 87 (1) :119-128 (2006)
Background Reference 03
Ravn, L.S., et al. Am. J. Cardiol. 96 (3) :405-407 (2005)
Background Reference 04
Yang, Y., et al. Am. J. Hum. Genet. 75 (5) :899-905 (2004)
Other Product Names
Potassium voltage-gated channel subfamily E member 1-like protein, AMME syndrome candidate gene 2 protein, KCNE1L, AMMECR2
Tested Applications
WB
Physical Properties
Liquid