NPW Antibody

• Background:

  NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog. [provided by RefSeq].

• NCBI Gene ID:

  283869

• Swiss Prot:

  Q8N729

• Accession Number:

  Q8N729

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NPW antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the C-terminal region of human NPW.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  18 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NPW

• NCBI Official Name:

  Neuropeptide W

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Luttrell, L.M. Mol. Biotechnol. 39 (3) :239-264 (2008)

• Background Reference 02:

  Singh, G., et al. Br. J. Pharmacol. 148 (8) :1033-1041 (2006)

• Other Product Names:

  Neuropeptide W, Preproprotein L8, hPPL8, Neuropeptide W-23, NPW23, hL8, Neuropeptide W-30, NPW30, hL8C, NPW, PPL8, PPNPW

• Tested Applications:

  WB

• Physical Properties:

  Liquid