ABCD2 Antibody

CAT: 0223-64-036Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-64-036Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ABCD2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters.
NCBI Gene ID
225
Swiss Prot
Q9UBJ2
Accession Number
Q9UBJ2
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ABCD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the Central region of human ABCD2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ABCD2
NCBI Official Name
ATP-binding cassette sub-family D member 2
NCBI Organism
Homo sapiens
Background Reference 01
Saito, A., et al. J. Hum. Genet. 54 (6) :317-323 (2009)
Background Reference 02
Maier, E.M., et al. Biochem. Biophys. Res. Commun. 377 (1) :176-180 (2008)
Background Reference 03
Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)
Other Product Names
ATP-binding cassette sub-family D member 2, Adrenoleukodystrophy-like 1, Adrenoleukodystrophy-related protein, hALDR, ABCD2, ALD1, ALDL1, ALDR, ALDRP
Tested Applications
WB
Protein ID
12643305
Physical Properties
Liquid

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