ABCA2 Antibody

• Background:

  The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  20

• Swiss Prot:

  Q9BZC7

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 2307-2466 of human ABCA2 (NP_997698.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Immunology, Innate Immunity, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse brain

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 270kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:1000

• Symbol:

  ABCA2

• NCBI Official Name:

  ATP-binding cassette, sub-family A (ABC1), member 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ABCA2, ATP-binding cassette, sub-family A (ABC1), member 2, ABC2, MGC129761, sub-family A, OTTHUMP00000064733, KIAA1062

• Tested Applications:

  WB

• Physical Properties:

  Liquid