CHAT Antibody

• Background:

  CHAT is an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer disease.

• NCBI Gene ID:

  1103

• Swiss Prot:

  P28329

• Accession Number:

  P28329

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CHAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-128 amino acids from the N-terminal region of human CHAT.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  83 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CHAT

• NCBI Official Name:

  Choline O-acetyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shaffer, J.R., et al. Nutr Metab Cardiovasc Dis (2010) In press

• Background Reference 02:

  Beck, M., et al. Cell Tissue Res. 338 (1) :37-51 (2009)

• Background Reference 03:

  Need, A.C., et al. Eur. J. Hum. Genet. 17 (7) :946-957 (2009)

• Other Product Names:

  Choline O-acetyltransferase, CHOACTase, ChAT, Choline acetylase, CHAT

• Tested Applications:

  WB, IF

• Protein ID:

  281185509

• Physical Properties:

  Liquid