MORG1 Antibody

• Background :

  MORG1 is a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome.

• NCBI Gene ID :

  84292

• Swiss Prot :

  Q9BRX9

• Accession Number :

  Q9BRX9

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This MORG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-154 amino acids from the Central region of human MORG1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  34 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  WDR83

• NCBI Official Name :

  WD repeat domain-containing protein 83

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Haase, D., et al. Neurosci. Lett. 455 (1) :46-50 (2009)

• Background Reference 02 :

  Hopfer, U., et al. J. Biol. Chem. 281 (13) :8645-8655 (2006)

• Background Reference 03 :

  Vomastek, T., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (18) :6981-6986 (2004)

• Other Product Names :

  WD repeat domain-containing protein 83, Mitogen-activated protein kinase organizer 1, MAPK organizer 1, WDR83, MORG1

• Tested Applications :

  WB

• Protein ID :

  74761224

• Physical Properties :

  Liquid