NUPL2 Antibody

• Background:

  Required for the export of mRNAs containing poly (A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.

• NCBI Gene ID:

  11097

• Swiss Prot:

  O15504

• Accession Number:

  O15504

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NUPL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-115 amino acids from the N-terminal region of human NUPL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  45 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  NUPL2

• NCBI Official Name:

  Nucleoporin-like protein 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kendirgi, F., et al. Mol. Biol. Cell 16 (9) :4304-4315 (2005)

• Background Reference 02:

  Sasaki, M., et al. Genomics 85 (5) :641-653 (2005)

• Background Reference 03:

  Le Rouzic, E., et al. J. Biol. Chem. 277 (47) :45091-45098 (2002)

• Background Reference 04:

  De Noronha, C.M., et al. Science 294 (5544) :1105-1108 (2001)

• Other Product Names:

  Nucleoporin-like protein 2, NLP-1, NUP42 homolog, Nucleoporin hCG1, NUPL2, CG1

• Tested Applications:

  WB

• Physical Properties:

  Liquid