BRS3 Antibody

• Background:

  Mammalian bombesin-like peptides (see MIM 137260) are widely distributed in the central nervous system as well as in the gastrointestinal tract, where they modulate smooth-muscle contraction, exocrine and endocrine processes, metabolism, and behavior. They bind to G protein-coupled receptors on the cell surface to elicit their effects. Bombesin-like peptide receptors include gastrin-releasing peptide receptor (MIM 305670), neuromedin B receptor (MIM 162341), and bombesin-like receptor-3 (BRS3) (Ohki-Hamazaki et al., 1997) .

• NCBI Gene ID:

  680

• Swiss Prot:

  P32247

• Accession Number:

  P32247

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This BRS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human BRS3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  44 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  BRS3

• NCBI Official Name:

  Bombesin receptor subtype-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, Y., et al. Cell Biol. Int. 31 (12) :1495-1500 (2007)

• Background Reference 02:

  Tan, Y.R., et al. Biochem. J. 405 (1) :131-137 (2007)

• Background Reference 03:

  Hou, X., et al. Lung Cancer 54 (2) :143-148 (2006)

• Background Reference 04:

  Ross, M.T., et al. Nature 434 (7031) :325-337 (2005)

• Other Product Names:

  Bombesin receptor subtype-3, BRS-3, BRS3

• Tested Applications:

  WB

• Protein ID:

  416726

• Physical Properties:

  Liquid