DBC1 Antibody

• Background :

  DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.

• NCBI Gene ID :

  1620

• Swiss Prot :

  O60477

• Accession Number :

  O60477

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This DBC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the N-terminal region of human DBC1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  89 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  BRINP1

• NCBI Official Name :

  BMP/retinoic acid-inducible neural-specific protein 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Koyama, S., et al. Biochem. Biophys. Res. Commun. 392 (3) :357-362 (2010)

• Background Reference 02 :

  Gronbaek, K., et al. Mod. Pathol. 21 (5) :632-638 (2008)

• Background Reference 03 :

  Louhelainen, J.P., et al. Oncogene 25 (16) :2409-2419 (2006)

• Background Reference 04 :

  Izumi, H., et al. Hum. Mol. Genet. 14 (8) :997-1007 (2005)

• Other Product Names :

  BMP/retinoic acid-inducible neural-specific protein 1, Deleted in bladder cancer protein 1, BRINP1, DBC1, DBCCR1, FAM5A

• Tested Applications :

  WB

• Physical Properties :

  Liquid