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HBA2 Antibody

CAT: 0223-63-935Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-63-935Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
NCBI Gene ID
30393040
Swiss Prot
P69905
Accession Number
P69905
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This HBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Symbol
HBA1
NCBI Official Name
Hemoglobin subunit alpha
NCBI Organism
Homo sapiens
Background Reference 01
Sessa, R., et al. Am. J. Hematol. 85 (2) :143-144 (2010)
Background Reference 02
Sharma, V., et al. Hematology 14 (5) :297-300 (2009)
Background Reference 03
Waye, J.S., et al. Hemoglobin 33 (6) :519-522 (2009)
Background Reference 04
Roy, P., et al. Hemoglobin 33 (6) :486-491 (2009)
Other Product Names
Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain, HBA1
Tested Applications
WB, IHC-P, Flow
Protein ID
57013850
Physical Properties
Liquid

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